Cannabidiol as an Intervention for Addictive Behaviors: A Systematic Review of the Evidence

As a consumer learning about CBD oil online, it’s important to consider the current evidence while also recognizing the need for further research in this area. When determining the appropriate dosage for CBD, consider factors like your weight, metabolism, and the specific health concern you’re addressing. It’s also important to choose high-quality CBD products from reputable sources and follow their recommended dosing guidelines. Understanding the potential presence of THC in certain CBD products is crucial for making informed choices about what you consume. Familiarize yourself with labeling and independent testing processes to ensure that your chosen CBD product meets your specific needs and preferences. The cycle of addiction often leads individuals to prioritize obtaining and using the substance over other responsibilities or activities.

• However, ongoing studies are needed to fully understand its effects on addiction.
• Very recently, Chesworth and Karl exhaustively explored CBD actions (10 mg/kg, i.p.) on the acquisition, consolidation, reconsolidation, extinction, and drug-primed reinstatement of cocaine (15 mg/kg) in the CPP paradigm.
• However, research has found that 70% of CBD products contain significantly more THC than their labels suggest.
• Research has shown that CBD is not considered physically addictive, unlike other substances like opioids or nicotine.
• Evidence also indicated that it might have benefits in the treatment of tobacco and cannabis addiction.
• Although the Farm Bill had no effect on state-level cannabis programs, it led to a “hempslosion” of sorts, giving licensed growers the green light to cultivate and transfer hemp-derived products across state lines for commercial purposes.

What is the difference between hemp and cannabis CBD?

The endocannabinoid system is like our body’s operating system—it affects neurotransmitters that bind to receptors and impact pain, mood, appetite, sleep, and how we feel, move and react. Phytocannabinoids is cannabidiol addictive derived from plants mimic our body’s natural systems as their chemical makeup is similar to endocannabinoids. CBD is a common cannabinoid in cannabis, which is actually a group of flowering plants.

• CBD may alleviate some of the distress experienced in chronic pain, although exactly how it does this isn’t clear.
• All the authors critically reviewed and approved the final version of the article.
• Also, keep in mind that the FDA has not approved nonprescription CBD products, and some products may be inaccurately labeled.

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An interesting fact about cannabinoids is that even THC is not physically addictive. Addiction experts estimate that 91% of marijuana users never become problematic, meaning that 9% will form improper habits around the use of the plant, which may generate some form of abuse. All these interactions seem promising when it comes to easing withdrawal symptoms and reducing the risk of addiction. Still, there’s one more thing we’d like to cover before we move on to the benefits of CBD for addicted individuals. Researchers point to cannabidiol as the potential anti-inflammatory, neuroprotectant, antioxidant, and seizure suppressant.

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• Studies have shown promising results in using CBD to help manage cravings and reduce drug-seeking behaviors, making it an area of interest for further exploration.
• The effects of CBD were examined during the maintenance and extinction phases of SA and during cue-induced reinstatement.
• “A lot of cannabidiol that’s available for public consumption right now is cannabidiol mixed with a bunch of other stuff from cannabis. It’s not pharmaceutical-grade cannabidiol,” Dr Gururajan said.
• Additionally, children and adolescents should use caution when considering CBD due to the potential impact on brain development.
• Those who try to kick their habit can experience severe, sometimes life-threatening withdrawal symptoms, including tremors, pain in the bones and muscles, throbbing headache, nausea, vomiting, and depression.
• Many cultures, including the ancient Egyptians, used the cannabis plant and its derivatives for healing, and cannabis was most likely one of the first plants cultivated for the purpose of making cloth.

These include Australia, Canada, Switzerland, the United Kingdom, and the United States of America. Morgan et al studied the impact of CBD on nicotine addiction by conducting a randomized, double-blind, placebo-controlled study on 24 smokers who wished to stop smoking.33 https://ecosoberhouse.com/ Two groups received either a CBD inhaler (400 μg/inhalation) or a placebo inhaler. They were told to use the inhaler whenever they felt the urge to smoke, to assess daily cigarette and inhaler use, and to monitor their craving once daily for 1 week.

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In 2018, the Food and Drug Administration (FDA) approved Epidiolex, the first pure-CBD anti-seizure treatment. The FDA approved Epidiolex for treating rare forms of epilepsy, including Dravet syndrome and Lennox-Gastuaut syndrome. In a 2018 clinical trial, 72 children and 60 adults with treatment-resistant epilepsy received 5–50 milligrams per kilogram of body weight (mg/kg) of CBD daily.

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If you are thinking about trying CBD, discuss it with your doctor first. Be sure to tell your healthcare provider about any other medications you might be taking in order to prevent any potential drug interactions. Watch for side effects and don’t take more than the dose that your doctor recommends. Current evidence suggests that CBD use does not lead to addiction and that the substance may have a number of health benefits. However, it is also important to be aware that CBD does have some potential side effects. In addition to mental health benefits, some research indicates that CBD might be helpful for reducing pain, relieving nausea, and treating inflammation.

Neurobiological Mechanisms Involved in CBD-Mediated Regulation of Addiction

It differs from its cannabinoid counterpart, THC, in that it does not produce a high or any intoxicating effects. They also ruin the reputation of people like her and the products she passionately believes in after she used CBD, at her mother’s urging, to deal with chronic pain after she was hit by a car as a pedestrian in downtown Austin years ago, she said. Last month, Republican Lt. Gov. Dan Patrick ordered the Texas Senate to look into potentially banning the hemp products that contain THC, and investigate strict regulations for retailers across Texas. Since consumable hemp was legalized in Texas , the number of retail registrations for consumable hemp products has exploded in the state.

Some states have legalized CBD, so be sure to check state laws, especially when traveling. Also, keep in mind that the FDA has not approved nonprescription CBD products, and some products may be inaccurately labeled. If you live in a state that hasn’t yet legalized medical cannabis or these products are unavailable, you can still benefit from products containing industrial hemp-derived CBD. Cannabis-derived CBD products may be more effective than those from hemp, but industrial hemp-derived CBD still provides many health benefits.

However, the same group demonstrated that CBD (single 800 mg dose) reduced attentional bias after a period of tobacco abstinence without improving craving or withdrawal (Hindocha et al., 2018). Recently, a preclinical study was conducted to analyze the effects of CBD (10 and 30 mg/kg) in mice exposed to an animal model of pharmacologically precipitated nicotine withdrawal. Interestingly, CBD abolishes memory impairment and microglial reactivity induced by nicotine withdrawal (Saravia et al., 2019).